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High deductible insurance linked to delayed advanced cancer diagnosis
Time to diagnosis of metastatic cancer increased by nearly 5 months for patients whose employers switched them to high-deductible health insurance...
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Transplanted pig hearts functioned normally in deceased persons on ventilator support
The experimental procedure could enable future widespread use of xenotransplantation to treat end-stage heart failure.
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Bimekizumab calms psoriatic arthritis in phase 3 ‘BE’ trials
The dual interleukin-17 inhibitor was effective both in patients for whom TNF inhibitors failed and those who had never received a biologic...
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Bimekizumab tames active ankylosing spondylitis in BE MOBILE 2
The dual IL-17A and IL-17F inhibitor improved function, quality of life, and objective measures of inflammation, compared with placebo, in...
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European AxSpA guidelines reflect recent changes in drug therapy
While there are similarities between some of the recommendations promulgated on each side of the Atlantic, there are significant differences and...
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TNF placental transfer makes little difference in offspring infections
“Our data are reassuring as we saw no strong signal, which suggests that there is no need to switch the mother’s drugs.”
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High maternal, fetal morbidity rates in SLE pregnancies
Despite steady declines in maternal and fetal mortality among pregnant women with systemic lupus erythematosus, maternal and fetal morbidities...
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Upadacitinib effective against nonradiographic AxSpA
The JAK inhibitor was effective and safe for patients with rheumatologist-diagnosed axial spondyloarthritis that did not meet radiographic...
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Poorest children at higher risk for PICU admissions, death
Children in poor neighborhoods may be more likely to receive care in lower-quality hospitals or may be treated differently from other children...
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Age, skin cancer risks for ICI-induced bullous pemphigoid identified
“It’s harder to understand why a presumably antibody-mediated side effect would be more likely to have that cross-reactivity where the tumor...
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Preop nivolumab plus chemo ‘a quantum leap’ in NSCLC therapy
The combination resulted in significantly longer event-free survival.